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3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems

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Mitochondrial lipid peroxidation detection For mitochondrial lipid peroxidation detection, cells were divided into PBS (0.1%), DMSO (0.1%), RSL-3 (7.89 μM) and RSL-3 (7.89 μM) + Lipro-1 (1 μM) groups