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These rats then received co-injections 6–10 of (a) fentanyl (125 μg/kg, IV) + vehicle, (b) L-NAC (500 μmol/kg, IV) + fentanyl (125 μg/kg, IV) or (c) L-NACme (500 μmol/kg, IV) + fentanyl (125 μg/kg, IV) given 90 s apart