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MedPAC stated that their recommended update to IPPS and OPPS payment rates of current law plus 1 percent may not be sufficient to ensure the financial viability of some Medicare safety-net hospitals with a poor payer mix

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In this process, GSH is constantly oxidized to GSSG by the enzyme glutathione peroxidase.To maintain the intracellular redox balance, GSH is replenished through the reduction GSSG by glutathione reductase enzyme