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In such cases, MMA concen­trations in urine should be adjusted for creatinine excretion (Norman & Morrison, 1993) and the ratio of urinary MMA to creatinine (uMMA/C) applied to assess B12 status

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What the Authoritative Sources Say About B12 Deficiency and Supplementation The National Institutes of Health Office of Dietary Supplements publishes the most thorough citation-backed overview of vitamin B12 — its role in red blood cell formation and neurological function, the populations most at risk for deficiency (older adults, people on long-term metformin or proton pump inhibitors, vegetarians and vegans, people who have had gastric bypass surgery), and the recommended daily intake at each life stage