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Among 23 patients where methemoglobin levels were regularly measured on DDDCT and HDDCT, 65.2% (15/23) were less than 5%, 26% (6/23) were between 5 and 10%, and 8.6% (2/23) were between 11–20%, as long as patients took the maximum dose of methylene blue (300 mg PO BID) with other antioxidants (glutathione, Vit C, Vit E, NADH) [173]

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Since integrated -omics studies have just started, further investigation will provide more detailed information on holistic networks of sulfur metabolism

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