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The authors compare multiple senolytic strategies including FOXO4-DRI, dasatinib plus quercetin, navitoclax, and fisetin, evaluating mechanisms of action, selectivity profiles, and safety considerations for each approach

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Moreover, a recent meta-analysis-based retrospective study indicated an elevation in blood homocysteine level as a risk factor for patients with CVD and End-stage Renal Disease ESRD, not treated with any folic acid supplementation [78, 81]

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