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However, most of the data is over ten years old and relies on BDNF-levels in peripheral blood mononuclear cells (PBMC) or serum, as BDNF-levels in Cerebrospinal fluid (CSF) are low and ultra-sensitive immunoassays are necessary for its reliable detection (60)

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Research has uncovered associations between healthy eating patterns, including higher dietary levels of vitamin B12, and a low incidence of depression