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In 2016, the National Institute on Drug Abuse reported an age-adjusted cocaine-mediated death rate of 52.4% in the USA

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The Short Answer Peptide therapy can be appropriate for selected patients, but no clinician can accurately call the entire category “safe” or “unsafe.” Risk depends on the specific peptide, formulation, dose, route, treatment goal, evidence base, medical history, other medications, and quality of follow-up