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Before the consensus on nomenclature, the protein had been called nonselenium GSH peroxidase (86), aiPLA 2 (38), 1-Cys Prdx (34), antioxidant protein 2 (AOP2) (75), Clara cell protein 26 (CC26), and p29 (47), whereas the gene in addition to ORF6 (64) has been called LTW4 (30) and keratinocyte growth factor (KGF)-regulated gene 1 (24)
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In particular, a large amount of GSH is known to play a critical role in cellular redox maintenance and antioxidative systems 8,10