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Rather than covering general pharmacological effects, we examine how NAC affects neuromodulatory pathways that contribute to its therapeutic effects

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Lastly, the duration of the Bruce-protocol GXT may not have been long enough to elicit an improvement in non-protein substrate utilization, future studies may wish to test the effect of the patches on non-protein substrate utilization in recreational endurance athletes (runners, cyclists, swimmers, etc.) during prolonged submaximal aerobic exercise