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Chloral is a competitive substrate of ALDH with a slow k cat and IC 50 values ranging from 1 to 10 μM (Poon et al., 2002)
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However, more recent analyses of the platelets from subjects with G6PD deficiency have shown that these cellular elements, in response to oxidative stress, can also undergo vesciculation, shedding microparticles with potential procoagulant activity
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