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Both models exhibited this non-discreet morphology with continuous enlargement in contrast to the nodular self-limited growth most common with human CN, and interestingly, the findings were mostly associated with gonadally intact male pigs, suggesting some role for androgens in CN tumorigenesis within this model

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Figure 2 Figure 3 The patient was treated with 500 μg mecobalamin intramuscular injection three times a week, supplemented with vitamin B12, vitamin B2, folic acid and some traditional Chinese medicine as adjuvant therapy