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NbGSTU4 binds to the 3′ untranslated region (UTR) of BaMV positive sense (+) RNA in a GSH-dependent manner and is necessary for efficient viral RNA replication i.e., production of a viral negative sense (–) RNA and then new genomic (+) RNA (Chen et al., in vivo BaMV replication and in vitro (–) RNA synthesis, while oxidative agents inhibit in vitro (–) RNA synthesis (Chen et al., Resistance-Inducing Symbiotic Microorganisms and Plant GSTs Non-pathogenic, symbiotic bacteria and fungi living in the rhizosphere of plants can be highly beneficial to plants attacked by pathogenic microorganisms