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After NSAIDs or insulin overdose or cuprizone (a neurotoxin that induces multiple sclerosis like lesion in rat model) or large bowel resection, encephalopathies were attenuated along with gastrointestinal, liver and vascular injuries

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The award for the Nobel Prize for Physiology and Medicine was for the discovery of the ‘anti-pernicious anaemia factor’ from their experiments with liver in the diet