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Moreover, controversial findings were made in oxidative stress markers’ levels, since besides increased SOD activity, levels of plasma malondialdehyde, erythrocyte lipid peroxidation, and catalase were not different from those in the control group

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Metabolic flux analysis showed that the levels of 13 C-labeled metabolites, including glutamate (GLU), α-ketoglutarate (α-KG), succinate (SUCC), fumarate (FUM), malate (MAL), citrate (CIT), pyruvate (PYR), oxaloacetate (OAA), phosphoenolpyruvate (PEP), lactate (LAC), and ribulose-5-phosphate (R5P), were significantly higher in the 18F-FDG-PET/CT-negative gastric cancer cells (KATO-III and MKN-45) compared to control cells (Fig