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Administration less frequent than twice weekly likely allows complete dissipation of synaptic changes between doses, preventing the cumulative structural modifications that constitute Dihexa’s therapeutic mechanism

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On the other hand, clinical data suggest a high analgesic efficacy after intra-articular administration: as many as 87.5% of patients with knee pain experienced improvement following BPC-157 treatment, both as monotherapy and in combination with thymosin beta 4 (TB4) [201,202]

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