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Full reconstitution guide → · Advanced calculator → Dosing & Reconstitution Guide A single practical dilution with once-weekly maintenance dosing, step by step Standard Approach (2 mL = 5 mg/mL) Reconstitute: Add 2.0 mL bacteriostatic water to one 10 mg vial → final concentration 5 mg/mL (5,000 mcg/mL)

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Using T cell leukemia as a model, we confirmed that the canonical CD39/CD73 pathway is flanked by another set of surface molecules leading to the production of ADO, but using NAD + as a leading substrate ( + -glycohydrolase/CD38, the ectonucleotide pyrophosphatase/phosphodiesterase 1 (NPP1)/CD203a and the 5′-ectonucleotidase (5′NT)/CD73