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Consistent with previous reports, the amounts of Cys-Gly were ∼50% higher in older flies ( To conclude, this study revealed that the age-related dampening of circadian rhythms in clock genes underlie the age-related loss of rhythmicity of cellular redox

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in fact results, obtained in a study of GSH systemic availability, showed that it is not possible to enhance GSH level to a clinically beneficial extent even by the oral administration of a high single dose of 3 g of GSH [17]