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TB-500 (Thymosin Beta-4 fragment) has preclinical wound-healing data but no peer-reviewed research specifically supporting its use for intestinal permeability or 'leaky gut.' What it may miss It may not cover eligibility, contraindications, medication interactions, lab history, or dose escalation

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Marketing authorisation and BNF advice In general the doses, indications, cautions, contra-indications, and side-effects in the BNF reflect those in the manufacturers’ data sheets or Summaries of Product Characteristics (SPCs) which, in turn, reflect those in the corresponding marketing authorisations (formerly known as Product Licences)