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Appraisal of CagriSema for treatment of obesity and type 2 diabetes 1.Advantages of CagriSema Available data suggest that the HbA1c-lowering efficacy of the combination of cagrilintide and semaglutide was higher than that achieved by each drug alone (table 1) [10]

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: Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts