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Dietary antioxidant quercetin overcomes the acquired resistance of Sorafenib in Sorafenib-resistant hepatocellular carcinoma cells through epidermal growth factor receptor signaling inactivation

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Melatonin binds to G-protein-coupled receptors (MT1 and MT2) in the hypothalamus, pars tuberalis, and suprachiasmatic nucleus of the brain (among other structures) as well as receptors in the immune system, kidneys, and vessels [5]