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Although there are few studies demonstrating the efficacy of these drugs in companion animal IBD, a recent study in a rat model of IBD (colitis induced by 2,4,6-trinitrobenzene sulfonic acid) suggests that tylosin is effective at decreasing inflammation
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By day 52, cumulative Dox exposure reached 30 mg/kg, at which point significant LV dilation and functional failure are known to occur, consistent with prior models [1]
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