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A mechanistic marker that is species-divergent cannot carry a cross-species mechanistic argument, and the history of beta-3-directed pharmacology is a cautionary case study rather than a supporting one
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indicated that the peptide reduced over 50% of body weight gain in these laboratory models compared to controls, with heightened lipolytic activity observed within the adipose tissues of exposed rats, alongside an absence of notable disruptions in insulin sensitivity in these experimental settings
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