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However, in our setup, the measurement of higher droplet velocities was unattainable due to the viscosity of the oil phase and the limited cross-section area of the channel, which restrict the maximum velocity of the fluid/droplet at the selected rotation speeds

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Steric hindrance from the increased side-chain volume of E14 Cagri and R17 Cagri promotes a shift of the α-helix of Cagri away from ECL2 and a slight expansion of the peptide binding pocket at the extracellular side of the CTR TM domain, relative to those observed with rAmy/San385-bound AMYR complexes