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Tolerance-inducing therapies in coeliac disease — mechanisms, progress and future directions | Nature Reviews Gastroenterology & Hepatology

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Moreover, evidence supporting EGCG’s neuroprotective effects via BBB-mediated anti-neuroinflammation and reduction of oxidative stress includes: (i) EGCG enhances dopamine neuron activity in the gut, decreases serotonin levels in the colon, and increases hippocampal 5-hydroxytryptamine levels by enhancing intestinal permeability (215–217)