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For example, the cytosolic glutathione pool may well be less oxidized than that measured in extracts because a substantial amount of the GSSG generated by oxidative stress is shipped to the vacuole, possibly by ABCC transporters (Martinoia et al., Figure 5 presents an overview that attempts to integrate some of the different processes that are likely to be involved in oxidative stress-driven changes in glutathione status

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Violin plots were generated in Loupe browser using the normalized sum of expression of HMOX1, SOD1, GPX4, and PRDX5