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The tryptophan 5-hydroxylase 1, crucial for the synthesis of serotonin (5-HT), and tyrosine hydroxylase, a rate-limiting enzyme in the production of dopamine, adrenaline, and noradrenaline, are both positively regulated by SCFAs (175, 176)
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Understanding that purging is normal (and often a sign the treatment is working) helps users push through this uncomfortable phase rather than abandoning treatment prematurely
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