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In the course of this exploration, we pinpoint therapeutic targets unearthed in the repair program, thereby prompting the contemplation of potential strategies aimed at reinstating both the function and integrity of the intestinal barrier in the treatment of IBD

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Behavioral testing was followed by biochemical analyses on colon, faces, serum, cerebellum, and prefrontal cortex, assessing tryptophan metabolites, serotonin (5-HT) pathway intermediates, neurotransmitters (GABA, glutamate, dopamine, acetylcholine) via UPLC, UPLC-TQD, and ELISA, alongside gut microbiota profiling through 16S r RNA sequencing