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the secondary endpoint was change in UPDRS at 52 weeks

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In addition to S-RBD and Nucleocapsid protein, we also attached different viral components such as S1 subunit of spike protein, S1 subunit N terminal domain (NTD) and S2 extracellular domain (ECD) onto the magnetic beads and tested IgG levels specific to those viral proteins to compare the antibody levels they detect