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Pica et al., 2012, 2016)

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Two noncanonical c-Myc binding sites (CACATG, E box) are present in the human GCLC promoter at −559/−554 and −500/−495 and together with ARE4, are responsible for H 2 O 2 -induced GCLC promoter activity (Benassi et al., 2006)