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Refrigeration (2 to 8 degrees C) further slows the Arrhenius-governed rate of any residual hydrolysis and oxidative reactions
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Telomere shortening in human cells is accelerated by increased oxidative stress (Lombard et al., 2005), yet species with long telomeres often exhibit lower oxidative-protection mechanisms, which may represent an evolutionary trade-off that favors constitutive telomerase activity and reduced dependence on energetic antioxidant defenses (Gomes et al., 2011)
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