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Presence of Ca 2+ /CaMKK in adipocytes correspondingly regulates the activation of AMPK (Gormand et al., 2011)
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High-dose or prolonged pyridoxine supplementation can also lead to alterations in other nutrient levels, for example, extended use of large doses has been associated with reduced serum folate concentrations in some reports, which suggests a need to monitor nutritional balance during long-term therapy
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