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In the enzyme’s active center, where the Glu, Try, and Asp residues form a highly nucleophilic region, oxidation of the active site selenocysteine (Rr-SeH) or cysteine (R-SH) occurs after binding the peroxide, which leads to the formation of a selenenic acid (Pr-SeOH) derivative in selenium-containing isoforms

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If the purge feels intense, you might want to start with a lower dose of collagen and gradually increase it as your body adapts