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Simani L, Ramezani M, Darazam IA, Sagharichi M, Aalipour MA, Ghorbani F, et al
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In one study, one week of kava administration (75 mg/kg) induced an increase in acetylcholinesterase (AchE) activity in the adult male rat striatum [85], while 4-week administration resulted in significant decreases in the enzymatic activity in the cortex, hippocampus, and striatum [85]
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