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People with mild iron-deficiency anemia may not sense a problem while those with moderate to severe anemia can experience many symptoms, including: Tiredness or fatigue Weakness Headaches Pale or yellow skin Cold hands and feet Hair loss Irregular or fast heartbeat Chest pain Shortness of breath Dizziness or lightheadedness Pounding or whooshing sound in the ears Sore or smooth tongue Brittle nails Many of these symptoms can be innocuous and transient, or they could signal anemia or another health problem